Manchester United vs Chelsea prediction and preview: Old Trafford hosts a massive Premier League clash with injuries, lineups, and key battles to watch.
Manchester United vs Chelsea Prediction & Match Preview
It doesn’t get much bigger than 🔴 Manchester United vs Chelsea 🔵 under the lights at Old Trafford. The Premier League’s most drawn fixture is back this weekend, but both sides desperately need more than a point. For United, it’s about survival. For Chelsea, it’s about making a statement.

United’s Struggles Under Amorim
Life hasn’t been easy for Ruben Amorim. The Manchester derby last weekend ended in a 3-0 defeat, leaving United with just four points from four games—their worst Premier League start since 1992-93.
The stats make grim reading: only 31 points from 31 matches under Amorim, the lowest return of any top-flight team in that period. Whispers of players “losing faith” in his methods haven’t helped either. Still, the Portuguese coach insists he won’t change his philosophy, even as pressure builds.
Old Trafford has been a fortress of sorts against Chelsea—they haven’t lost to the Blues at home in the league since 2013. That record is one of the few bright sparks United fans can cling to heading into Saturday.

Chelsea’s Unbeaten League Start
Chelsea, meanwhile, look like a team still learning but definitely progressing. Enzo Maresca’s side are unbeaten in the league so far (W2 D2), scoring nine goals in four matches. They looked sharp in wins against West Ham and Fulham, though the midweek Champions League trip to Bayern Munich brought a 3-1 defeat.
That said, Chelsea have shown resilience. Cole Palmer is in fine form, Reece James is close to full fitness, and Joao Pedro has been directly involved in more Premier League goals this season than anyone else.
Saturday will also have extra spice with Alejandro Garnacho—a recent £40m signing from United—possibly making his full Chelsea debut against his old club. Imagine the headlines if he scores.

Injury Concerns & Predicted Lineups
United are still without Lisandro Martinez, while doubts remain over Cunha, Mount, and Dalot. A big call for Amorim will be whether to throw new goalkeeper Senne Lammens straight into the action.
Chelsea will miss Romeo Lavia, Benoit Badiashile, and Mudryk (suspended). However, the return of Reece James could see Maresca shuffle the midfield, with Enzo Fernandez and Moises Caicedo pushing deeper to allow Palmer freedom in attack.
Possible Lineups
- Manchester United: Lammens; Yoro, De Ligt, Shaw; Mazraoui, Casemiro, Fernandes, Dorgu; Mbeumo, Amad, Sesko
- Chelsea: Sanchez; James, Chalobah, Tosin, Cucurella; Fernandez, Caicedo; Neto, Palmer, Garnacho; Pedro

Prediction
United need this more than Chelsea—but pressure doesn’t always bring performances. Chelsea look sharper, more balanced, and have a fresher belief under Maresca.
Our call? 🔴 Manchester United 0-2 Chelsea 🔵.
The Blues might finally end their Old Trafford hoodoo!